Sunderland remain in striking distance in fourth as they prepare to welcome Norwich, aiming to extend their unbeaten home run to 11 games against a Canaries side who are winless in seven away games since September.
Blackburn head to managerless Millwall in search of a seventh straight league win while Middlesbrough will try to keep their grip on a play-off place as they make the longest trip of the weekend to second-bottom Plymouth, where Michael Carrick will face-off against former Man United and England teammate Wayne Rooney.
The battle at the bottom takes centre stage on Saturday lunchtime, too.
Ruben Selles will hope his Hull City side move off the bottom with a first win since his arrival when they welcome Swansea, while third-bottom Portsmouth aim to bounce back from a drubbing at Derby as they host Coventry.
Stoke will try to extend their five point cushion over the foot of the table as they head to Sheffield Wednesday in another 12:30 GMT kick-off.
Resurgent QPR and Preston will both be trying to make it seven games unbeaten and stay clear of the drop-zone as they meet in West London at 15:00 GMT.
Rs head coach Marti Cifuentes told Radio London: “This is a relentless, ruthless league and you need to be on top of your qualities every time.
“It’d be a huge mistake as a team, as a club, to think that everything is fine. Football is about small margins, right now those small margins are helping us to get points and of course the team keeps growing.
“But the reality is there are a lot of things we need to improve and hopefully everyone can understand that.”
West Brom will launch a new unbeaten streak following their defeat at Watford as they host Bristol City on Sunday afternoon.
